The paper published in Burns Open has presented the case of a four day-old neonate suffering from life threatening burns, involving 40% total body surface area burn. The patient received 260 cm2 of denovoSkin, covering 20% TBSA, as part of a clinical trial sub-study in Italy.
The management of such cases represents an unprecedented challenge.
The published paper is based on a one-year follow-up of the patient, and these results deliver further proof of concept that denovoSkin can be successfully applied in pediatric severe burns.
Specifically, the case report has noted that:
- Clinically, denovoSkin grafted areas show a matured skin after 3–6 months with minimal or no detectable scarring, whereas conventional grafting was not yet matured and mostly associated with moderate to massive hypertrophic scarring.
- denovoSkin yields close to normal skin in terms of softness, elasticity, pliability, growth, and mechanical robustness.
The full case report can be read online, see link below.
