Cutiss

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Series B financing oversubscribed

CUTISS closes series B funding – Target of CHF 20 million oversubscribed

Zurich, Switzerland, June 29 2020 – CUTISS AG, an innovative Swiss Life Science Company aiming to provide patients that suffer from large and deep skin defects with an automatically produced, personalized skin tissue therapy, denovoSkin™, today announced it has successfully closed its series B financing round. The fundraising aiming at CHF 20 million was eventually oversubscribed.
The proceeds will allow CUTISS to further progress denovoSkin™, the Company’s unique personalized skin technology to treat skin defects, i.e. due to burns. Upcoming key inflection points include the completion of the ongoing clinical phase II trials, the scale-up of the manufacturing at the Biotechnopark in Zurich-Schlieren, and the successful implementation of a prototype machine for the automated production of large quantities of skin from a small piece of healthy skin. It is CUTISS’ ambition to file for market authorization with denovoSkin™ in Switzerland and in the European Union in 2022.
Dr. Daniela Marino, Chief Executive Officer and Co-Founder of CUTISS AG, commented: “We feel very lucky and privileged that we have closed an oversubscribed series B financing round. We will invest these proceeds circumspectly, aiming at improving burn patients’ lives.”
Giammaria Giuliani, Co-Founder of Gisev Family office and Member of the Board of Directors of CUTISS, added: “It has been an honor acting as lead investor for this series B financing round. The support by the Wyss Foundation as well as new and existing private investors and family offices demonstrates the potential many investors see in CUTISS’ vision and strategy.”

About CUTISS AG
CUTISS is a Swiss Life Science Company, spin-off of the University of Zurich, developing personalized skin graft technologies for the treatment of a large spectrum of skin defects. Its lead product candidate, denovoSkin™, has been tested in a phase I clinical trial on pediatric patients at the University Children’s Hospital in Zurich. Phase II studies are currently ongoing in Switzerland and the European Union and are partially funded by Wyss Zurich. denovoSkin™ has received Orphan Drug Designation for the treatment of burns by Swissmedic, EMA and FDA. In addition, denovoSkin™ aims to improve life quality of elective (reconstructive treatments) patients as well and it can further be developed in terms of complexity by adding pigmentation.

Contact
CUTISS AG, CEO Daniela Marino, +41 76 230 80 46, info@cutiss.swiss, www.cutiss.swiss

Logo CUTISS News final

Series B Financing Round successfully secured
with CHF 18.7 Mio.

CUTISS with successful series B financing round – funds raised so far sum-up to CHF 18.7 million

Zurich, Switzerland, June 4 2020 – CUTISS AG, an innovative Swiss Life Science Company aiming to provide patients that suffer from large and deep skin defects with an automatically produced, personalized skin tissue therapy, denovoSkin™, today announced it has successfully secured its series B financing round. Funds raised so far sum-up to CHF 18.7 million. The financing round was led by Giammaria Giuliani (Gisev Family Office), seconded by the Wyss Foundation and supported by new and existing private investors and family offices. The series B financing round aiming at up to CHF 20 million in total is still ongoing; its final closing is expected for June 15 2020.

The proceeds will allow CUTISS to further progress denovoSkin™, the Company’s unique personalized skin technology to treat skin defects, i.e. due to burns. Upcoming key inflection points include the completion of the ongoing clinical phase II trials, the scale-up of the manufacturing at the Biotechnopark in Zurich-Schlieren, and the successful implementation of a prototype machine for the automated production of large quantities of skin from a small piece of healthy skin. It is CUTISS’ ambition to file for market authorization with denovoSkin™ in Switzerland and in the European Union in 2022.

In 2018, CUTISS raised CHF 11.2 million in a series A financing round that included Business Angels and Family Offices as well as Giammaria Giuliani (Gisev Family Office), Yellowstone Holding, and the Zürcher Kantonalbank (ZKB). In addition, a total of CHF 4 million were granted by Innosuisse and the European Commission (non-dilutive).

Dr. Daniela Marino, Chief Executive Officer and Co-Founder of CUTISS AG, commented: “We are thrilled and honored about the great interest our series B financing round has received from both private and professional investors, especially on the backdrop of the current challenging times. We thank our existing shareholders for their continued support and our new investors for their commitment and trust.”

About CUTISS AG
CUTISS is a Swiss Life Science Company, spin-off of the University of Zurich, developing personalized skin graft technologies for the treatment of a large spectrum of skin defects. Its lead product candidate, denovoSkin™, has been tested in a phase I clinical trial on pediatric patients at the University Children’s Hospital in Zurich. Phase II studies are currently ongoing in Switzerland and the European Union and are partially funded by Wyss Zurich. denovoSkin™ has received Orphan Drug Designation for the treatment of burns by Swissmedic, EMA and FDA. In addition, denovoSkin™ aims to improve life quality of elective (reconstructive treatments) patients as well and it can further be developed in terms of complexity by adding pigmentation.

Contact
CUTISS AG, CEO Daniela Marino, +41 76 230 80 46, info@cutiss.swiss, www.cutiss.swiss

Gérard Ber appointed as additional Board Member

CUTISS AG announces additional Member of the Board of Directors

Zurich, Switzerland, May 28 2020 – CUTISS AG, an innovative Swiss Life Science Company aiming to provide patients that suffer from large and deep skin defects with an automatically produced, personalized skin tissue therapy, denovoSkin™, today announced it has further enhanced its Board of Directors with Gerard Ber as newly elected, additional and independent Member of the Board.

At the recent Annual Shareholder Meeting 2020 of CUTISS, Dr. Gerard Ber was elected as additional and independent Member of the Board of the Company for a term of one year, thus further strengthening its Board of Directors. Gerard has been acting as Co-Founder, Chief Operating Officer and Member of the Board of Advanced Accelerator Applications, an innovative radiopharmaceutical Company based in France that was acquired by Novartis in 2018. Before, he held positions as Export Area Manager for Western Europe at OM Pharma Switzerland (Vifor Pharma) in Geneva and Director of Marketing and Commerce for CIS Bio International/ORIS in Paris. Today, Gerard is Life Science Entrepreneur and Member of the Board of Directors of, among others, Ymabs (New York). He studied Pharmacy at the University of Grenoble (France). Dr. Gerard Ber is a Swiss citizen.

Daniela Marino, CEO and Co-Founder of CUTISS AG, commented: “We are pleased and honored that Gerard Ber has accepted becoming an independent Member of our Board, thereby offering his valuable and broad know-how of the Life Science industry to our emerging Company.”

About CUTISS AG
CUTISS is a Swiss Life Science Company, spin-off of the University of Zurich, developing personalized skin graft technologies for the treatment of a large spectrum of skin defects. Its lead product candidate, denovoSkin™, has been tested in a phase I clinical trial on pediatric patients at the University Children’s Hospital in Zurich. Phase II studies are currently ongoing in Switzerland and the European Union and are partially funded by Wyss Zurich. denovoSkin™ has received Orphan Drug Designation for the treatment of burns by Swissmedic, EMA and FDA. In addition, denovoSkin™ aims to improve life quality of elective (reconstructive treatments) patients as well and it can further be developed in terms of complexity by adding pigmentation.

Contact
CUTISS AG, CEO Daniela Marino, +41 76 230 80 46, info@cutiss.swiss, www.cutiss.swiss

TEDx Zurich talk by CEO Daniela Marino

Watch our CEO Daniela Marino talk on stage for TEDx Zurich Women about how much mothers and managers have in common.

Female managers with children have the great chance to train at home how to be better managers and to train at work how to be better mothers. Managers that are also mothers are tired, yes, but not unfocussed, they do not underperform. They do not need to be discouraged or discriminated against. Instead they need full support because being mothers and managers makes them beautiful creatures that have much more to give to society, future generations and the industry. As a scientist, a young entrepreneur and a mother, Daniela’s mission is to foster healthy and sustainable growth of both her family and her business – she believes with creativity, sacrifice, and passion, marvelous things can be achieved. Despite wanting to be a researcher since she was 7 years old, her curiosity, determination and risk tolerance made her leave her scientific career to build a life science start-up, CUTISS AG, with the vision to bring personalized skin tissue therapy to help patients with skin defects. This talk was given at a TEDx event using the TED conference format but independently organized by a local community. Learn more at https://www.ted.com/tedx

UZH article “From Lab to Life”

Fabienne Hartmann-Fritsch still feels most at home in the lab, even though she now spends more time in front of her PC than inspecting Petri dishes. In 2017, the biologist founded the spin-off CUTISS together with four other UZH scientists. Once clinical trials are complete, the spin-off plans to roll out personalized skin tissue therapy on the market – in other words, customized human skin grown in the lab. During her doctoral studies at the University Children’s Hospital Zurich, Hartmann-Fritsch started specializing in planning and executing clinical research projects involving humans and dealing with the legal framework. The transition from pure research to (communications) management was an easy one for her. “It’s immensely gratifying to now be able to apply the results of years’ worth of lab work,” she says. The innovative product that is supposed to increase the quality of life of people suffering from skin defects is called denovoSkin. In the second trial phase, the researchers will now test the safety and effectiveness of the skin replacement in various clinics. For Hartmann-Fritsch, this means extensive talks with medics, sponsors and the authorities.

Text: Alice Werner
Picture: Frank Brüderlin

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